Certified Ophthalmic Medical Technologist (COMT) Practice Exam

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What is the consequence of blocked retinal vessels in sickle cell retinopathy?

  1. Increased vision

  2. Promotion of blood vessel growth

  3. Hazy vision

  4. Reduced eye pressure

The correct answer is: Promotion of blood vessel growth

In sickle cell retinopathy, the blockage of retinal vessels due to sickle-shaped red blood cells leads to hypoxia or reduced oxygen supply to the retinal tissue. In response to this lack of oxygen, the body often triggers the formation of new blood vessels in an attempt to restore the oxygen supply to the deprived areas. This process is known as angiogenesis, and it's the body's way of compensating for the insufficient blood flow caused by the blocked vessels. However, the newly formed vessels are often weak and leak, which can lead to further complications, including bleeding and vision impairment. In contrast, the other options do not accurately reflect the physiological response or effect of blocked retinal vessels in this condition. Increased vision isn’t a likely outcome, as the blockage typically leads to vision problems. Hazy vision may occur; however, it is more of a symptom rather than a direct consequence of the blockages. Reduced eye pressure is generally not associated with vessel blockage; in fact, ocular complications can often lead to increased pressure. Thus, the consequence of blocked retinal vessels in sickle cell retinopathy predominantly involves the promotion of blood vessel growth as the body attempts to adapt to the condition.